Infections Immune Disorders, Compensatory Mechanisms

Infections Immune Disorders, Compensatory Mechanisms
Infections Immune Disorders, Compensatory Mechanisms
For the purpose of this assignment, I have chosen to write about Systemic Lupus Erythematosus and Psoriasis. Systemic Lupus Erythematosus (SLE) is an autoimmune disease that causes inflammation in different tissues of the body. Autoimmune diseases affect approximately 8% of the population, affecting more women than men (Arcangelo, Peterson, Wilbur, & Reinhold, 2017). Also, autoimmune diseases occur when the body’s immune system attacks its own tissues. The diagnosis of SLE is based on a combination of clinical findings and laboratory evidence. Familiarity (Medscape, 2017). Systemic Lupus Erythematosus has the potential to be life-threatening and the symptoms of SLE include fatigue, pain or swelling in joints, skin rashes, and fevers as shown on Infections Immune Disorders, Compensatory Mechanisms literature (CDC, 2018).
Infections Immune Disorders, Compensatory Mechanisms
The treatment for Systemic Lupus Erythematosus consists mainly of drugs that prevent inflammation including hydroxychloroquine and corticosteroids. approved by the FDA for the (CDC,2018). Additionally, systemic lupus erythematous (SLE) often require treatment with intense immunosuppression. For example, high dose corticosteroids with the alkylating agent cyclophosphamide, antimetabolites such as methotrexate, azathioprine, or biological therapy such as rituximab or belimumab (Berman, & Belmont, 2017). Therefore, it is vital to educate the patients of the potential side effects of these drugs including the risk for infection, inclusive of bacteria, viruses, and fungi (Berman, & Belmont, 2017).
On the other hand, psoriasis is a chronic autoimmune skin disease that is characterized by rapid growth of skin cells. Some of the symptoms of Psoriasis include patches of thick red skin and silvery scales. The areas where these patches are more commonly found are the elbows, knees, scalp, lower back, face, palms, and soles of feet (CDC, 2016).
Treatments for psoriasis range from creams and ointments for affected areas and ultraviolet light therapy to drugs, for example, methotrexate. Topical calcipotriol and betamethasone dipropionate cutaneous foam consider the safest and effective topical treatments for mild-to-moderate psoriasis. However, adherence to the treatment is crucial for its effectiveness. Appropriate patient education is important for a patient to follow the treatment recommendation (Svendsen, Andersen, Andersen, & Andersen, 2018).
Arcangelo, V. P., Peterson, A. M., Wilbur, V. & Reinhold, J. A.  (Eds.). (2017).
Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA:
Lippincott Williams & Wilkins.
Berman, N., & Belmont, H. M. (2017). Disseminated cytomegalovirus infection complicating
active treatment of systemic lupus erythematosus: an emerging problem. Lupus, 26(4),
431-434. doi:10.1177/0961203316671817
Laureate Education, Inc. (Executive Producer). (2012b). Antimicrobials. Baltimore, MD: Author.
Lupus. (2018, January 08). Retrieved March 15, 2018, from
Psoriasis. (2016, February 09). Retrieved March 14, 2018, from
Svendsen, M. T., Andersen, F., Andersen, K. H., & Andersen, K. E. (2018). Can an app
supporting psoriasis patients improve adherence to topical treatment? A single-blind
randomized controlled trial. BMC Dermatology, 18(1), 2. doi:10.1186/s12895-018-0071-
Systemic Lupus Erythematosus (SLE). (2017, December 06). Retrieved March 14, 2018, from
Discussion Questions (DQ)

Initial responses to the DQ should address all components of the questions asked, including a minimum of one scholarly source, and be at least 250 words.
Successful responses are substantive (i.e., add something new to the discussion, engage others in the discussion, well-developed idea) and include at least one scholarly source.
One or two-sentence responses, simple statements of agreement, or “good post,” and responses that are off-topic will not count as substantive. Substantive responses should be at least 150 words.
I encourage you to incorporate the readings from the week (as applicable) into your responses.

Weekly Participation

Your initial responses to the mandatory DQ do not count toward participation and are graded separately.
In addition to the DQ responses, you must post at least one reply to peers (or me) on three separate days, for a total of three replies.
Participation posts do not require a scholarly source/citation (unless you cite someone else’s work).
Part of your weekly participation includes viewing the weekly announcement and attesting to watching it in the comments. These announcements are made to ensure you understand everything that is due during the week.

APA Format and Writing Quality

Familiarize yourself with APA format and practice using it correctly. It is used for most writing assignments for your degree. Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for APA paper templates, citation examples, tips, etc. Points will be deducted for poor use of APA format or absence of APA format (if required).
Cite all sources of information! When in doubt, cite the source. Paraphrasing also requires a citation.
I highly recommend using the APA Publication Manual, 6th edition.

Use of Direct Quotes

I discourage overutilization of direct quotes in DQs and assignments at the Masters’s level and deduct points accordingly.
As Masters’s level students, it is important that you be able to critically analyze and interpret information from journal articles and other resources. Simply restating someone else’s words does not demonstrate an understanding of the content or critical analysis of the content.
It is best to paraphrase content and cite your source.

LopesWrite Policy

For assignments that need to be submitted to LopesWrite, please be sure you have received your report and Similarity Index (SI) percentage BEFORE you do a “final submit” to me.
Once you have received your report, please review it. This report will show you grammatical, punctuation, and spelling errors that can easily be fixed. Take the extra few minutes to review instead of getting counted off for these mistakes.
Review your similarities. Did you forget to cite something? Did you not paraphrase well enough? Is your paper made up of someone else’s thoughts more than your own?
Visit the Writing Center in the Student Success Center, under the Resources tab in LoudCloud for tips on improving your paper and SI score.

Late Policy

The university’s policy on late assignments is 10% penalty PER DAY LATE. This also applies to late DQ replies.
Please communicate with me if you anticipate having to submit an assignment late. I am happy to be flexible, with advance notice. We may be able to work out an extension based on extenuating circumstances.
If you do not communicate with me before submitting an assignment late, the GCU late policy will be in effect.
I do not accept assignments that are two or more weeks late unless we have worked out an extension.
As per policy, no assignments are accepted after the last day of class. Any assignment submitted after midnight on the last day of class will not be accepted for grading.


Communication is so very important. There are multiple ways to communicate with me: 

Questions to Instructor Forum: This is a great place to ask course content or assignment questions. If you have a question, there is a good chance one of your peers does as well. This is a public forum for the class.
Individual Forum: This is a private forum to ask me questions or send me messages. This will be checked at least once every 24 hours.

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