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Assignment NURS 6501N-38 Advanced Pathophysiology-Endocrine System

Assignment: NURS 6501N-38 Advanced Pathophysiology-Endocrine System

NURS 6501N-38 Advanced Pathophysiology-Endocrine System

Disorders of the endocrine system have a significant impact on the body. Consider the effects of unmanaged diabetes. Kali Collins, a 10-year-old Colorado girl, helped prevent a potentially fatal accident after her mother, Erin Bolefahr, went into diabetic shock while behind the wheel. After Erin began driving erratically, Kali phoned for help. Police were able to locate the vehicle and provide medical care to an unresponsive Erin (Huffington Post, 2012). If Erin’s diabetes had been properly managed, her daughter would have never been in such immediate danger. This case emphasizes the importance of properly identifying, treating, and managing diabetes. With diabetes and its associated alterations presenting serious medical complications, it is essential for advanced practice nurses to have a strong understanding of this endocrine disorder. In the clinical setting, patients with diabetes and other endocrine disorders will require extensive patient education and supervised care.

This week you examine the pathophysiology of diabetes. You also explore the impact of patient factors on the disorder.

Kali Collins, 10-year-old Colo. girl, saves family by calling 911 when mom goes into diabetic shock while driving. (2012, March 6). Retrieved from http://www.huffingtonpost.com/2012/03/06/kali-collins-10-years-old_n_1323056.html

Learning Objectives

Students will:
  • Compare the pathophysiology of diabetes mellitus and diabetes insipidus
  • Evaluate the impact of patient factors on diabetes
  • Understand and apply key terms, concepts, and principles related to alterations of the endocrine system

Learning Resources

Huether, S. E., & McCance, K. L. (2017). Understanding pathophysiology (6th ed.). St. Louis, MO: Mosby.

  • Chapter 18, “Mechanisms of Hormonal Regulation” à This chapter explores mechanisms of hormonal regulation and the structure and function of the endocrine glands. It provides a foundation for examining alterations of the endocrine system, as well as the effects of aging on the endocrine glands.
  • Chapter 19, “Alterations of Hormonal Regulation” à This chapter begins with an explanation of the mechanisms of hormonal alterations. It then discusses alterations of the hypothalamic-pituitary system, thyroid function, parathyroid function, endocrine pancreas, and adrenal function. It also covers the pathophysiology, clinical manifestations, and evaluation and treatment of type 1 and type 2 diabetes.


Hammer, G. G. , & McPhee, S. (2014). Pathophysiology of disease: An introduction to clinical medicine. (7th ed.) New York, NY: McGraw-Hill Education.

  • Chapter 17, “Disorders of the Parathyroids & Calcium & Phosphorus Metabolism” à This chapter explores the anatomy, histology, and associated mechanisms of the parathyroid glands, bone, vitamin D, and C cells. It then examines various disorders involving altered regulation of parathyroids, calcium, and phosphorous metabolism.
  • Chapter 18, “Disorders of the Endocrine Pancreas” à This chapter explores the anatomy, histology, and physiology of the endocrine pancreas. It then covers the clinical presentation, etiology, pathophysiology, and clinical manifestations of endocrine pancreas disorders such as diabetes mellitus.

Chapter 19, “Disorders of the Hypothalamus & Pituitary Gland” à This chapter covers the structure and function of the hypothalamus and pituitary glands. It then explores disorders relating to alterations of the hypothalamus and pituitary glands.

  • Chapter 20, “Thyroid Disease” àThis chapter explains thyroid hormones, including how they are formed and secreted. It then examines thyroid diseases such as hyperthyroidism, hypothyroidism, and goiters.

American Diabetes Association. (2012). Retrieved from http://www.diabetes.org/

The Endocrine Society. (2012). Retrieved from http://www.endo-society.org/

The Hormone Foundation. (2012). Retrieved from http://www.hormone.org/

Discussion: Diabetes

According to the American Diabetes Association (2011), 25.8 million children and adults have been diagnosed with diabetes in the United States. Approximately 2 million more are diagnosed every year, with another 79 million people considered to be in a pre-diabetes state. These millions of people are at risk of several alterations, including heart disease, stroke, kidney failure, neuropathy, and blindness. Since diabetes has a major impact on the health of millions of people around the world, it is essential for nurses to understand the pathophysiology and associated alterations of this disorder. In this Discussion, you compare two types of diabetes—diabetes mellitus and diabetes insipidus.

To Prepare

Assignment NURS 6501N-38 Advanced Pathophysiology-Endocrine System

Assignment NURS 6501N-38 Advanced Pathophysiology-Endocrine System

Click here to ORDER an A++ paper from our MASTERS and DOCTORATE WRITERS:Assignment: NURS 6501N-38 Advanced Pathophysiology-Endocrine System

  • Review Chapter 19 in the Huether and McCance text and Chapter 18 in the McPhee and Hammer text. Identify the pathophysiology of diabetes mellitus and diabetes insipidus. Consider the similarities and differences between resulting alterations of hormonal regulation.
  • Select two of the following patient factors: genetics, gender, ethnicity, age, or behavior. Think about how the factors you selected might impact the diagnosis and prescription of treatment for these two types of diabetes.

NURS 6501N-38 Advanced Pathophysiology-Endocrine System

By Day 3

Post an explanation of the pathophysiology of diabetes mellitus and diabetes insipidus. Describe the differences and similarities between resulting alterations of hormonal regulation. Then explain how the factors you selected might impact the diagnosis and prescription of treatment for these two types of diabetes.

Read a selection of your colleagues’ responses.


NURS 6501N-38 Week Nine Discussion


A collection of hormone producing glands make-up the endocrine system. The endocrine system’s hormones are involved in regulating growth and development, metabolism, mood, sexual function, sleep, and other functions as well (Zimmermann, 2016). When there is an alteration of the endocrine system hormone levels become elevated, or are too low, usually indicating changes in the bodies fluid balance, infection, or physiologic stress (Huether, & McCance, 2017). The topic of this paper is diabetes mellitus (DM) and diabetes insipidus (DI). Understanding of DM and DI entails the understanding of the endocrine system and the feedback mechanisms for insulin, glucagon, and somatostatin work to maintain glucose stores in the body.

NURS 6501N-38 Advanced Pathophysiology-Endocrine System

Pathophysiology of Diabetes Mellitus

Huether and McCance (2017), describe diabetes mellitus as a “group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both” (p. 471) and classifies DM into four categories. Three of the four categories include type 1, type 2, and gestational. DM is diagnosed from one of the several tests performed on two separate occasions including glycosylated hemoglobin (HbA1c), fasting plasma glucose, 2-hour plasma glucose levels during oral glucose tolerance testing, or by random glucose levels in an individual with symptoms (Huether, & McCance, 2017, p. 471).

Consider the effects of unmanaged diabetes. Kali Collins, a 10-year-old Colorado girl,

Important information for writing discussion questions and participation

Hi Class,

Please read through the following information on writing a Discussion question response and participation posts.

Contact me if you have any questions.

Important information on Writing a Discussion Question

  • Your response needs to be a minimum of 150 words (not including your list of references)
  • There needs to be at least TWO references with ONE being a peer reviewed professional journal article.
  • Include in-text citations in your response
  • Do not include quotes—instead summarize and paraphrase the information
  • Follow APA-7th edition
  • Points will be deducted if the above is not followed

Participation –replies to your classmates or instructor

  • A minimum of 6 responses per week, on at least 3 days of the week.
  • Each response needs at least ONE reference with citations—best if it is a peer reviewed journal article
  • Each response needs to be at least 75 words in length (does not include your list of references)
  • Responses need to be substantive by bringing information to the discussion or further enhance the discussion. Responses of “I agree” or “great post” does not count for the word count.
  • Follow APA 7th edition
  • Points will be deducted if the above is not followed

Welcome to class

Hello class and welcome to the class and I will be your instructor for this course. This is a -week course and requires a lot of time commitment, organization, and a high level of dedication. Please use the class syllabus to guide you through all the assignments required for the course. I have also attached the classroom policies to this announcement to know your expectations for this course. Please review this document carefully and ask me any questions if you do. You could email me at any time or send me a message via the “message” icon in halo if you need to contact me. I check my email regularly, so you should get a response within 24 hours. If you have not heard from me within 24 hours and need to contact me urgently, please send a follow up text to.

I strongly encourage that you do not wait until the very last minute to complete your assignments. Your assignments in weeks 4 and 5 require early planning as you would need to present a teaching plan and interview a community health provider. I advise you look at the requirements for these assignments at the beginning of the course and plan accordingly. I have posted the YouTube link that explains all the class assignments in detail. It is required that you watch this 32-minute video as the assignments from week 3 through 5 require that you follow the instructions to the letter to succeed. Failure to complete these assignments according to instructions might lead to a zero. After watching the video, please schedule a one-on-one with me to discuss your topic for your project by the second week of class. Use this link to schedule a 15-minute session. Please, call me at the time of your appointment on my number. Please note that I will NOT call you.

Please, be advised I do NOT accept any assignments by email. If you are having technical issues with uploading an assignment, contact the technical department and inform me of the issue. If you have any issues that would prevent you from getting your assignments to me by the deadline, please inform me to request a possible extension. Note that working fulltime or overtime is no excuse for late assignments. There is a 5%-point deduction for every day your assignment is late. This only applies to approved extensions. Late assignments will not be accepted.

If you think you would be needing accommodations due to any reasons, please contact the appropriate department to request accommodations.

Plagiarism is highly prohibited. Please ensure you are citing your sources correctly using APA 7th edition. All assignments including discussion posts should be formatted in APA with the appropriate spacing, font, margin, and indents. Any papers not well formatted would be returned back to you, hence, I advise you review APA formatting style. I have attached a sample paper in APA format and will also post sample discussion responses in subsequent announcements.

Your initial discussion post should be a minimum of 200 words and response posts should be a minimum of 150 words. Be advised that I grade based on quality and not necessarily the number of words you post. A minimum of TWO references should be used for your initial post. For your response post, you do not need references as personal experiences would count as response posts. If you however cite anything from the literature for your response post, it is required that you cite your reference. You should include a minimum of THREE references for papers in this course. Please note that references should be no more than 5 years old except recommended as a resource for the class. Furthermore, for each discussion board question, you need ONE initial substantive response and TWO substantive responses to either your classmates or your instructor for a total of THREE responses. There are TWO discussion questions each week, hence, you need a total minimum of SIX discussion posts for each week. I usually post a discussion question each week. You could also respond to these as it would count towards your required SIX discussion posts for the week.

I understand this is a lot of information to cover in 5 weeks, however, the Bible says in Philippians 4:13 that we can do all things through Christ that strengthens us. Even in times like this, we are encouraged by God’s word that we have that ability in us to succeed with His strength. I pray that each and every one of you receives strength for this course and life generally as we navigate through this pandemic that is shaking our world today. Relax and enjoy the course!

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